How do GLP-1 medications like semaglutide actually work in the body?

GLP-1 (glucagon-like peptide-1) is a hormone your body naturally makes after you eat. It helps control blood sugar, slows how quickly food leaves your stomach, and sends “fullness” signals to your brain. GLP-1 medications like semaglutide and tirzepatide mimic this hormone, leading to smaller portions, fewer cravings, and more stable blood sugar. Over time, this can translate into 15–20% body-weight reduction in clinical studies. For a deeper dive, read our article “What Is GLP‑1 and How It Helps With Weight Loss in Atlanta”.