How is semaglutide taken for weight loss?

For weight loss, semaglutide is usually taken as a once‑weekly subcutaneous injection using a pre‑filled pen into the abdomen, thigh, or upper arm. Some clinics also offer compounded semaglutide in vials. Your Atlanta‑area provider or clinic staff will show you exactly how to inject safely at home. There is also an oral version of semaglutide (Rybelsus) for diabetes, but the injectable form is more commonly used for weight loss.