How much weight can I realistically expect to lose with semaglutide?

In large clinical trials, patients on semaglutide 2.4 mg (the Wegovy dose) lost an average of 15–20% of their starting body weight over about 68 weeks when combined with diet and exercise. Real‑world results vary based on your starting weight, adherence, and lifestyle changes. Many Metro Atlanta patients report noticeable changes within the first 2–3 months as appetite and cravings decrease. For a detailed look at expected results, see our article “GLP‑1 Weight Loss Results: What to Expect in Atlanta”.